Article: Systemic Monocytic-MDSCs Are Generated from Monocytes and Correlate with Disease Progression in Breast Cancer Patients.
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Bergenfelz C; Larsson AM; von Stedingk K; Gruvberger-Saal S; Aaltonen K; Jansson S; Jernström H; Janols H; Wullt M; Bredberg A; Rydén L; Leandersson K
PLoS ONE, 2015
10.1371/journal.pone.0127028.t002
Table 2 Correlations between clinical parameters of patients with LRR/MBC and”normal” or”high” frequency of Mo-MDSCs of PBMCs (see <xref ref-type="fig" rid="pone.0127028.g003">Fig 3A</xref>).
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”Normal” Mo-MDSC
”High” Mo-MDSC
P-value
Mean age
62 ± 10 y
58 ± 10 y
0.3
Tumor type Ductal
11
10
0.99
Lobular
1
1
Other
1
1
NHG 1
1
0
0.41
2
5
4
3
5
1
Unknown
2
7
Tumor Size (T) T1
4
3
0.72
T2
5
2
T3
1
2
T4
1
1
Unknown
2
4
Node status (N) N0
5
2
0.22
N1
4
1
N2
2
4
Unknown
2
5
Hormone Receptor Status ER+
11
5
0.07
ER-
2
5
Unknown
0
2
PR+
8
6
0.94
PR-
5
4
Unknown
0
2
HER2 status HER2+
2
3
0.41
HER2-
8
5
Unknown
3
4
Adjuvant chemotherapy Yes
4
3
0.75
No
9
9
Type of recurrence Locoregional recurrence
2
0
0 .04
Distant recurrence
10
6
Distant metastasis at initial diagnosis
1
6
Number of metastatic sites 0-2
9
4
0.07
3-5
4
8
Metastatic site Lymph nodes
2
8
0 .009
Lung
4
4
0.9
Liver
2
6
0.06
Bone
9
11
0.16
Visceral
5
9
0.07
Bone-only
5
1
0.08
Time to recurrence 51 ± 50 m
52 ± 75 m
0.57
Inferred neuron-electrophysiology data values
Neuron Type
Neuron Description
Ephys Prop
Extracted Value
Standardized Value
Content Source
